Last update
4/19/2026

Overview

SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
USERS' SCORE
Good
Based on 11 Reviews
8
Supplement Facts
Serving Size:  3 Veg Capsules
Amount Per Serving
%DV
Calories
5
 
Total Carbohydrate
1.5 g
<1%**
Total Sugars
1.5 g
D-Mannose
1.5 g (1,500 mg)
📅 Last updated:

Top Medical Research Studies

We explored how D-mannose could help prevent urinary tract infections and discomfort in patients undergoing cystoscopy. In a well-structured study with 32 patients, those receiving D-mannose experienced significantly fewer UTIs and less severe urinary symptoms compared to those who did not receive treatment.

While the treatment showed promise by reducing the number of infections and pain, no major difference was found in overall quality of life scores between the groups. This indicates D-mannose could be beneficial for specific discomforts related to the procedure.
Read More
7
Yeast impacts sperm quality negatively
We examined how certain yeast strains affect male fertility, particularly by observing their influence on sperm quality.

Our research revealed that these yeast strains altered conventional sperm parameters like viability and motility when incubated together.

Interestingly, while functional parameters showed changes, these were not statistically significant. However, pretreating sperm with mannose did reduce the impact of the yeast, suggesting that the yeast's interaction with sperm is likely mediated through mannose receptors.
Read More
4
D-mannose has limited preventive effects
We considered how D-mannose and other lifestyle changes might help prevent recurrent urinary tract infections. Our review looked into various preventative measures, including hygiene and diet.

We found that D-mannose can potentially help by preventing harmful bacteria from sticking to the urinary tract. However, its effectiveness may vary based on the dosage. While these methods are generally well-tolerated, they are not guaranteed solutions.

We concluded that a mix of dietary adjustments and proper hydration could serve as an alternative to long-term antibiotic treatment.
Read More

Most Useful Reviews

9
Effective for prevention
31 people found this helpful
I initially experienced burning with D-Mannose, but this subsided as my body adjusted. Having suffered from recurrent UTIs and yeast infections due to antibiotic use, I was desperate for relief. After taking D-Mannose three times daily for seven months, I have had no UTIs, and my mother has seen similar results. Although she had initial discomfort, she also enjoys significant improvement without further antibiotic treatment. I highly recommend D-Mannose for those struggling with traditional remedies.
Read More
7.5
Works for yeast infections
7 people found this helpful
It works... enough said. I had periods with bladder spasms and UTI symptoms, unaware they were yeast-related. After eating wheat, I began experiencing discomfort while urinating. Taking the maximum dose of these while drinking plenty of water resolved the symptoms within two days. I was astonished at its effectiveness. I recommend it for both yeast-related and bacterial issues. It could save you on doctor visits and prescriptions.
Read More
10
Life-altering impact
5 people found this helpful
I had recurring yeast infections that affected my life. Instead of following my GP's advice on routine antibiotics, I found D-mannose, which transformed my experience. Since using it, I haven't had any yeast infections and now enjoy a carefree relationship. I’m incredibly grateful!
Read More

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Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
  • All Researches
We explored how D-mannose could help prevent urinary tract infections and discomfort in patients undergoing cystoscopy. In a well-structured study with 32 patients, those receiving D-mannose experienced significantly fewer UTIs and less severe urinary symptoms compared to those who did not receive treatment.

While the treatment showed promise by reducing the number of infections and pain, no major difference was found in overall quality of life scores between the groups. This indicates D-mannose could be beneficial for specific discomforts related to the procedure.
Read More
7
Yeast impacts sperm quality negatively
We examined how certain yeast strains affect male fertility, particularly by observing their influence on sperm quality.

Our research revealed that these yeast strains altered conventional sperm parameters like viability and motility when incubated together.

Interestingly, while functional parameters showed changes, these were not statistically significant. However, pretreating sperm with mannose did reduce the impact of the yeast, suggesting that the yeast's interaction with sperm is likely mediated through mannose receptors.
Read More
4
D-mannose has limited preventive effects
We considered how D-mannose and other lifestyle changes might help prevent recurrent urinary tract infections. Our review looked into various preventative measures, including hygiene and diet.

We found that D-mannose can potentially help by preventing harmful bacteria from sticking to the urinary tract. However, its effectiveness may vary based on the dosage. While these methods are generally well-tolerated, they are not guaranteed solutions.

We concluded that a mix of dietary adjustments and proper hydration could serve as an alternative to long-term antibiotic treatment.
Read More

User Reviews

USERS' SCORE
Good
Based on 11 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective for prevention
31 people found this helpful
I initially experienced burning with D-Mannose, but this subsided as my body adjusted. Having suffered from recurrent UTIs and yeast infections due to antibiotic use, I was desperate for relief. After taking D-Mannose three times daily for seven months, I have had no UTIs, and my mother has seen similar results. Although she had initial discomfort, she also enjoys significant improvement without further antibiotic treatment. I highly recommend D-Mannose for those struggling with traditional remedies.
Read More
7.5
Works for yeast infections
7 people found this helpful
It works... enough said. I had periods with bladder spasms and UTI symptoms, unaware they were yeast-related. After eating wheat, I began experiencing discomfort while urinating. Taking the maximum dose of these while drinking plenty of water resolved the symptoms within two days. I was astonished at its effectiveness. I recommend it for both yeast-related and bacterial issues. It could save you on doctor visits and prescriptions.
Read More
10
Life-altering impact
5 people found this helpful
I had recurring yeast infections that affected my life. Instead of following my GP's advice on routine antibiotics, I found D-mannose, which transformed my experience. Since using it, I haven't had any yeast infections and now enjoy a carefree relationship. I’m incredibly grateful!
Read More
7.5
Cured recurrent UTIs
4 people found this helpful
Great for UTI! TikTok led me here. This is my solution for recurrent UTIs—no more waiting for doctor appointments or suffering from yeast infections due to antibiotics. As soon as symptoms develop, I take these until they vanish. Caution is needed for diabetics, as this is a sugar type.
Read More
9
Avoids yeast infections
2 people found this helpful
Bye-bye UTI! This stuff works! Whenever I run out, I inevitably develop a UTI after sex. The antibiotics often lead to yeast infections, creating a cycle of issues. Instead of heading to the doctor for antibiotics, I take a high daily dose of this and drink some pure cranberry juice for three days. It’s far more effective than any antibiotic I’ve used.
Read More

Frequently Asked Questions

7.5
Amazing results
1 people found this helpful
D-Mannose is miraculous for treating yeast infections! I take two pills each day, and I have experienced significant relief and resolution of my issues. Thank goodness for this product!
2
Not helpful
D-Mannose did not assist with my yeast infections. I took two large capsules daily without any improvement in my condition.

References

  1. Quattrone C, Manfredi C, Napolitano L, Ferraro A, Distefano C, et al. D-Mannose Plus to Prevent Urinary Tract Infections and Discomfort after Cystoscopy: A Single-Center Prospective Randomized Pilot Study. Medicina (Kaunas). 2023;59. 10.3390/medicina59061165
  2. Castrillón-Duque EX, Puerta Suárez J, Cardona Maya WD. Yeast and Fertility: Effects of Activity of spp. on Sperm Quality. J Reprod Infertil. 2018;19:49. PubMed
  3. Armelle J. [Recurrent cystisis: No medicine preventive means]. Prog Urol. 2017;27:823. 10.1016/j.purol.2017.09.006
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